The Brotherhood has called for fresh protests nationwide on Thursday, raising the specter of renewed violence. It warned that the protests would grow in intensity, but gave no details. By early afternoon, dozens of Morsi supporters were blocking a main road near the site of the Nasr City camp, disrupting traffic.
The latest events in Egypt drew widespread condemnation from the Muslim world and the West, including the United States, Egypt's main foreign backer for over 30 years.
Nobel Peace Prize winner Mohamed ElBaradei resigned later Wednesday as Egypt's interim vice president in protest — a blow to the new leadership's credibility with the pro-reform movement.
Interim Prime Minister Hazem el-Beblawi said in a televised address to the nation that it was a "difficult day" and that he regretted the bloodshed but offered no apologies for moving against Morsi's supporters, saying they were given ample warnings to leave and he had tried foreign mediation efforts.
The leaders of Morsi's Muslim Brotherhood called it a "massacre." Several prominent Brotherhood figures were detained as police swept through the two sit-in sites, scores of other Islamists were taken into custody, and the future of the once-banned movement was uncertain.
Backed by helicopters, police fired tear gas and used armored bulldozers to plow into the barricades at the two protest camps on opposite ends of Cairo. Morsi's supporters had been camped out since before he was ousted by a July 3 coup that followed days of mass protests by millions of Egyptians demanding that he step down.
The smaller camp — near Cairo University in Giza — was cleared of protesters relatively quickly, but it took about 12 hours for police to take control of the main sit-in site near the Rabaah al-Adawiya Mosque in Nasr City that has served as the epicenter of the pro-Morsi campaign and had drawn chanting throngs of men, women and children only days earlier.