The FBI served a search warrant in connection with the investigation and police cordoned off a condominium building and the surrounding neighborhood in the shoreline city.
Condo resident Eric Bredow, a banker, said police told him the suspect in the car chase was one of his neighbors.
"I see the door to my building open and the FBI bomb squad in front of it," said Bredow, who said helicopters were flying overhead when he first went home
The chain-of-events began when the woman sped onto a driveway leading to the White House, over a set of barricades. When the driver couldn't get through a second barrier, she spun the car in the opposite direction, flipping a Secret Service officer over the hood of the car as she sped away, said B.J. Campbell, a tourist from Portland, Ore.
"This wasn't no accident. She was not a lost tourist," Campbell said later near the scene that had been blocked off with police tape.
Then the chase began.
"The car was trying to get away. But it was going over the median and over the curb," said Matthew Coursen, who was watching from a cab window when the Infiniti sped by him. "The car got boxed in and that's when I saw an officer of some kind draw his weapon and fire shots into the car."
One Secret Service member and a 23-year veteran of the Capitol Police were injured. Officials said they are in good condition and expected to recover.
Rep. Michael McCaul, R-Texas, who said he was briefed by the Homeland Security Department, said he did not think the woman was armed. "There was no return fire," he said.
A few senators between the Capitol and their office buildings said they heard the shots.