Republican candidate John Burnett, meanwhile, said New Yorkers deserve better than "a disgraced former governor" as comptroller.
And another contender, Kristin Davis, may make it difficult for Spitzer to avoid questions about his past. She was convicted of promoting prostitution and claims to have provided call girls to Spitzer, which hasn't been proven.
As for Weiner, when asked whether Spitzer was someone he could work with as mayor, he said yes but declined to comment further.
"I think everyone was surprised, but it hasn't changed my life at all," he said.
Associated Press writers Jon Gerberg and Jonathan Lemire in New York, and Michael Gormley and Michael Hill in Albany contributed to this report.